منابع مشابه
Response to therapy in breast cancer.
Increasing numbers of patients with newly diagnosed breast cancer receive primary systemic therapy followed by surgery. Histopathology provides an accurate assessment of treatment efficacy on the basis of the extent of residual tumor and regressive changes within tumor tissue. However, only approximately 20% of breast cancer patients achieve a pathologic complete response, a fact that necessita...
متن کاملUse of Apoptotic Biomarkers to Predict Response to Radiotherapy in Breast Cancer Patients
Introduction: To enhance radiation therapy efficiency it is crucial to implement an individual-based treatment. The aim of present study was to identify the mechanism of intrinsic apoptosis pathway on radiosensitivity and normal tissue complications caused by the radiotherapy. Materials and Methods: radiation-induced apoptosis in periphera...
متن کاملBiomarkers and response to therapy in breast cancer.
To the Editor: Yang and colleagues (1) describe an elegant study investigating molecular markers that are hypothesized to predict clinical benefit from the use of bevacizumab in breast cancer. This research is both timely and pertinent, given the ongoing questions surrounding the benefit conferred by the addition of bevacizumab to taxane-based chemotherapy in breast cancer (2). The data suggest...
متن کاملResponse to Adjuvant Endocrine Therapy in Breast Cancer
Purpose: Immunohistochemistry (lHC) is a newer technique for assessing the estrogen receptor (ER) status of breast cancers, with the potential to overcome many of the shortcomings associated with the traditional ligand-binding assay (LBA). The purpose of this study was to evaluate the ability of ER status determination by IHC, compared with LBA, to predict clinical outcomeespecially response to...
متن کاملPredictive factors for response to neoadjuvant therapy in breast cancer.
Within 2 decades, neoadjuvant therapy (NAT) has become a standard treatment option in breast cancer. The advantage of NAT is the ability to monitor the treatment effect. Pathological complete response (pCR) after NAT is a very good predictor for long-term outcome. Clinical factors, such as age and body mass index, as well as recently identified biomarkers can predict the chance of achieving a p...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2009
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.108.057240